In 1886, via NYT
869 President Street, between Seventh and Eighth Avenues, isn't just one of the most interesting houses in the neighborhood, it's one of the most interesting houses in the entire city. The work of little-known architect Henry Ogden Avery, it was constructed in 1885 and was almost immediately noted in the Brooklyn Eagle for being "very pecular, a wide departure from ordinary forms."
The 36-foot wide brick facade was designed to be as simple as possible, with two arched windows on the first floor, two oriel windows on the second, and three pairs of rectangular windows on the third. In a New York Times profile of the building from a few years ago, they note that "the oriels had slightly projecting rivet-head details, peculiar cockscomb-like trim on the tops, and strange angled poles supporting them from underneath — strange because builders had long since determined how to support such features without resorting to such devices."
The building's original owner was Stewart L. Woodford, politician and diplomat who served as lieutenant governor of New York from 1867 to 1868. The Mannix family moved in in the late 1920s, and redesigned the interior. Per the Times:
"The entry door is an iron swirl depicting a pair of peacocks; the vestibule behind is paneled in mottled azure- and oatmeal-colored tile. The main hall has an Art Deco cornice, but the living room is more French Renaissance, with a strap-work ceiling, heavily modeled plaster walls and a terra-cotta fireplace. The library is at first glance wood-paneled, in impeccable repair — but it is faux-painted and varnished plaster."

By the time the above photo was taken, in 1950, the building had been sold to the Columban Foreign Missionary Society, who used the space as a home for "transient and convalescent priests of the society," according to the photo's caption.
Since 1988, the home has been occupied by Madelyn Schloss and her husband Martin, an opthamologist, and they've spent the past few years completely renovating it. Surprisingly, brokers told Madelyn that the building's unorthodox interior might actually be a drawback: "They say it’s too bad, people really want the dark brownstone-style interiors,” she said.

The "peculiar cockscomb-like trim" has been removed from the tops of the oriels, but other than that the building, like so many others in this neighborhood, remains completely intact.